MAB1307
Mouse Anti-Human IgG1 Antibody, clone HP6001, Fc
clone HP6001, Chemicon®, from mouse
Synonyme(s) :
Anti-CD32, Anti-FCG2, Anti-FCGR2, Anti-FCGR2C, Anti-FcGRIIB, Anti-FcRII-c, Anti-FcgammaRIIb, Anti-IGFR2
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.46
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
secondary antibodies
Clone
HP6001, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Chemicon®
Technique(s)
ELISA: suitable
radioimmunoassay: suitable
western blot: suitable
Isotype
IgG2b
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... FCGR2B(2213)
Catégories apparentées
Spécificité
Human IgG1 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1- 100% human IgG subclass 2- 0.25% human IgG subclass 3- 0.01%
human IgG subclass 4-0.01% Isoelectric Focusing: mean pI 8.0
human IgG subclass 4-0.01% Isoelectric Focusing: mean pI 8.0
Immunogène
Epitope: Fc fragment
Application
Detect Human IgG1 using this Mouse anti-Human IgG1 Antibody, clone HP6001, Fc validated for use in ELISA, RIA & WB.
Research Category
Secondary & Control Antibodies
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
Fragment Specific Secondary Antibodies
This antibody employed as both a capture antibody and a detection antibody for human IgG1 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Liaison
Replaces: MABN1055
Forme physique
Format: Purified
Purified immunoglobulin. Liquid in 0.02 M Phosphate buffer, 0.25 M NaCl containing 0.1% sodium azide.
Stockage et stabilité
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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mAbs blocking immune checkpoints have emerged as important cancer therapeutics, as exemplified by systemic administration of the IgG1 anti-CD47 mAb that blocks the "don't eat me" pathway. However, this strategy is associated with severe toxicity. To improve therapeutic efficacy while
Bo Xu et al.
Nature communications, 12(1), 5908-5908 (2021-10-10)
Oncolytic herpes simplex virus-1 is capable of lysing tumor cells while alerting the immune system. CD47, in collaboration with SIRPα, represents an important immune checkpoint to inhibit phagocytosis by innate immune cells. Here we show locoregional control of glioblastoma by
Suzanne E Barbour et al.
Infection and immunity, 70(6), 2780-2786 (2002-05-16)
Several lines of evidence indicate that the monocytes of subjects with localized juvenile periodontitis (LJP) are functionally distinct from cells of age- and race-matched nonperiodontitis (NP) subjects. Among the abnormalities are the propensity to secrete large amounts of prostaglandin E(2)
R C Williams et al.
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To characterize immunologic specificity and possible antiidiotype activity of IgG anti-F(ab')2 in normal subjects as well as in patients with active and inactive systemic lupus erythematosus (SLE). IgG anti-F(ab')2 and anti-double-stranded DNA (anti-dsDNA) were affinity isolated from immunoadsorption columns of
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