ABN254

Anti-BAALC Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Brain and acute leukemia cytoplasmic protein, BAALC
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: rat, mouse
• Réactivité de l'espèce (prédite par homologie): human (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology)
• Technique(s): western blot: suitable
• Numéro d'accès NCBI: NP_079088
• Numéro d'accès UniProt: Q8WXS3
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... BAALC(79870)

Description

Description générale

Brain and acute leukemia cytoplasmic protein (BAALC) interacts with CAMK2A in a synaptic role at postsynaptic lipid rafts. BAALC is expressed by neural, hematopoietic, normal early progenitor cells and in the most immature type of blasts in acute leukemia. Isoform 2 and isoform 6 are also expressed in the brain.

Spécificité

This antibody recognizes the CAMK2A interaction domain of BAALC. This antibody should recognize all isoforms in uniprot.

Immunogène

Epitope: CAMK2A interaction domain

KLH-conjugated linear peptide corresponding to the CAMK2A interaction domain of human BAALC.

Application

Detect Brain & acute leukemia cytoplasmic protein using this rabbit polyclonal antibody, Anti-BAALC Antibody validated for use in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Qualité

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected BAALC in 10 µg of mouse brain tissue lysate.

Description de la cible

~22 kDa observed. Uniprot describes 6 isoforms produced by alternative splicing at ~19 kDa, ~16 kDa, ~9 kDa, ~8 kDa and ~6 kDa

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Mouse brain tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable