AB3530P
Anti-Epithelial Sodium Channel-α Antibody
Chemicon®, from rabbit
Synonyme(s) :
ENaC-alpha
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
polyclonal
Produit purifié par
affinity chromatography
Espèces réactives
rat
Fabricant/nom de marque
Chemicon®
Technique(s)
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... SCNN1A(6337)
Spécificité
Recognizes rat Epithelial Sodium Channel alpha (ENaC alpha). The immunogen shows no significant sequence homology with other ENaC subunits.
Immunogène
A 20 amino acid peptide sequence near the N-terminus of rat ENaC alpha (Linguela et al. 1993; Canessa et al.
1993; Snyder et al. 1994; Waldmann et al. 1995; Kreutz et al. 1997; Voilley et al.
1994; McDonald et al. 1994; Ludwig et al. 1998; Garty & Palmer 1997).
1993; Snyder et al. 1994; Waldmann et al. 1995; Kreutz et al. 1997; Voilley et al.
1994; McDonald et al. 1994; Ludwig et al. 1998; Garty & Palmer 1997).
Application
Anti-Epithelial Sodium Channel-α Antibody is an antibody against Epithelial Sodium Channel-α for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Neuroinflammation & Pain
Ion Channels & Transporters
Neuroinflammation & Pain
Western blot: 1-10 μg/mL using ECL and rat brain membrane preparations, see membrane preparation protocol under Technical Support\General Technical Info\General Methods at www.chemicon.com.
83-90kDa band is expected.
Optimal working dilutions must be determined by the end user.
83-90kDa band is expected.
Optimal working dilutions must be determined by the end user.
Description de la cible
83-90kDa
Forme physique
Affinity Purified immunoglobulin. Liquid in phosphate buffered saline, pH 7.4, containing 0.1% BSA and 0.1% sodium azide.
ImmunoAffinity Purified
Stockage et stabilité
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Remarque sur l'analyse
Control
Epithelial structures
Epithelial structures
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Gaizun Hu et al.
American journal of hypertension, 36(9), 509-516 (2023-05-12)
Our previous studies showed that renal medullary sphingosine-1-phosphate receptor 1 (S1PR1) mediated sodium excretion, high salt intake increased S1PR1 level, deoxycorticosterone acetate (DOCA) blocked high salt-induced S1PR1 in the renal medulla, and that conditional knockout of S1PR1 in the collecting
Noriatsu Shigemura et al.
Nutrients, 11(9) (2019-09-25)
The systemic renin-angiotensin system (RAS) is an important regulator of body fluid and sodium homeostasis. Angiotensin II (AngII) is a key active product of the RAS. We previously revealed that circulating AngII suppresses amiloride-sensitive salt taste responses and enhances the
Estrogen increases ENaC activity via PKC? signaling in renal cortical collecting duct cells.
Yusef, YR; Thomas, W; Harvey, BJ
Physiological Reports null
L R E Pedersen et al.
Acta physiologica (Oxford, England), 206(2), 142-149 (2012-06-12)
We wished to determine the effect of continuous β-receptor stimulation on alveolar fluid clearance and to elucidate the mechanisms behind this effect. Alveolar fluid clearance was measured in anaesthetized rats pretreated for 72 h with the β-agonist isoproterenol (200 μg kg(-1) h(-1) sc)
Eman Y Gohar et al.
Journal of the American Heart Association, 11(5), e020450-e020450 (2022-02-23)
Background Premenopausal women are less likely to develop hypertension and salt-related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined. Here, we determined whether female rats have a
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