AB3127

Anti-FLT-4 Antibody

Chemicon^®, from rabbit

• Synonyme(s) : VEGF Receptor-3
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: mouse
• Fabricant/nom de marque: Chemicon^®
• Technique(s): ELISA: suitable; western blot: suitable
• Numéro d'accès NCBI: NM_002020.3; NM_182925.3
• Numéro d'accès UniProt: P35916
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Flt4(14257)

Description

Spécificité

Recognizes mouse Flt-4 (mouse 1363-aa and human 1298-aa) a receptor protein tyrosine kinase. It is type 1 membrane protein, a receptor for VEGF-C and is expressed in adult lung, and liver, and in fetal liver, brain, intestine, and placenta. Flt-4 is also known as vascular endothelial growth factor receptor 3 (VEGFR3).

SPECIES REACTIVITIES: The peptide sequence used is relatively conserved in rat (85%) and human (73%) Flt-4/VEGFR3. No significant sequence homology is seen with VEGFR1, VEGFR2, or other tyrosine kinases. Antibody crossreactivity in other species is not established.

Immunogène

20 amino acid peptide sequence within the cytoplasmic, C-terminus of mouse Flt-4

Application

Detect FLT-4 using this Anti-FLT-4 Antibody validated for use in ELISA & WB.

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

Western blot: 1-10 μg/mL using ECL. The antibodies detected ~140 kDa band in rat liver extracts.

ELISA: 1:10,000-1:100,000, using 50-100ng of control peptide/well.

Optimal working dilutions must be determined by end user.

Forme physique

Liquid in PBS, containing 0.1% BSA. Affinity purified immunoglobulin.

Stockage et stabilité

Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze and thaw.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable