662045
Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb
liquid, Calbiochem®
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About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
liquid
Ne contient pas
preservative
Espèces réactives
human, rat, mouse
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
avoid repeated freeze/thaw cycles
Isotype
IgG
Conditions d'expédition
wet ice
Température de stockage
−70°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... UCP1(7350)
Description générale
Protein A purified rabbit polyclonal antibody. Recognizes the UCP-1 protein.
Recognizes the UCP-1 protein.
This Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb is validated for use in Immunoblotting for the detection of Uncoupling Protein-1 (UCP-1) (145-159).
Immunogène
Mouse
a synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1
Application
Immunoblotting (1:1000)
Avertissement
Toxicity: Standard Handling (A)
Forme physique
In PBS.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Autres remarques
Does not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Kozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Traci A Czyzyk et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(4), 1151-1159 (2009-11-18)
General opioid receptor antagonists reduce food intake and body weight in rodents, but the contributions of specific receptor subtypes are unknown. We examined whether genetic deletion of the kappa-opioid receptor (KOR) in mice alters metabolic physiology. KOR-knockout (KO) and wild-type
Marcella Funicello et al.
PloS one, 2(8), e683-e683 (2007-08-02)
Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white adipose tissue (WAT) of obese individuals. We herein characterized the
C L Plaisier et al.
Nutrition & diabetes, 2, e46-e46 (2013-03-01)
A better understanding of the processes influencing energy expenditure could provide new therapeutic strategies for reducing obesity. As the metabolic activity of the brown adipose tissue (BAT) and skeletal muscle is an important determinant of overall energy expenditure and adiposity
Laurent Vergnes et al.
The Journal of clinical endocrinology and metabolism, 101(11), 4440-4448 (2016-11-05)
Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that express uncoupling protein 1 within periadrenal (pADR) and omental (OME) fat depots. It has been hypothesized that this is due to adrenergic stimulation by catecholamines produced by the pheo tumors.
Traci A Czyzyk et al.
American journal of physiology. Endocrinology and metabolism, 305(2), E282-E292 (2013-05-30)
Obesity continues to be a global health problem, and thus it is imperative that new pathways regulating energy balance be identified. Recently, it was reported: (Hayashi K, Cao T, Passmore H, Jourdan-Le Saux C, Fogelgren B, Khan S, Hornstra I
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