05-572
Anti-Caspase 9 Antibody, clone 96-2-22
clone 96-2-22, Upstate®, from mouse
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
96-2-22, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Upstate®
Technique(s)
western blot: suitable
Isotype
IgG
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... CASP9(842)
Spécificité
Recognizes the proform and the active cleaved form of Caspase 9.
Immunogène
The N-terminal fragment of human Caspase 9 (amino acid residues 1-134)
Application
This Anti-Caspase 9 Antibody, clone 96-2-22 is validated for use in WB for the detection of Caspase 9.
Qualité
routinely evaluated by immunoblot on RIPA lysates from A431, Raji, or HFF cells
Description de la cible
46/34 kDa
Liaison
Replaces: 04-443
Forme physique
Format: Purified
Protein A Purified immunoglobulin in Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Remarque sur l'analyse
Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Heat shock protein inhibitors increase the efficacy of measles virotherapy.
Liu, C; Erlichman, C; McDonald, CJ; Ingle, JN; Zollman, P; Iankov, I; Russell, SJ; Galanis, E
Gene Therapy null
Morgan R Herod et al.
PloS one, 9(3), e90679-e90679 (2014-03-07)
Investigations into human norovirus infection, replication and pathogenesis, as well as the development of potential antiviral agents, have been restricted by the lack of a cell culture system for human norovirus. To date, the optimal cell culture surrogate virus model
Oncogene-dependent apoptosis is mediated by caspase-9.
Fearnhead, H O, et al.
Proceedings of the National Academy of Sciences of the USA, 95, 13664-13669 (1998)
Giuseppe Filomeni et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(1), 64-66 (2002-11-09)
Changes in the intracellular reduced/oxidized glutathione ratio (GSH/GSSG) are crucial reduction-oxidation (redox) events that trigger downstream proliferation or death responses. We investigated the molecular mechanisms underlying redox-mediated cell signaling upon an oxidative insult by treating U937 cells with exogenous nonpermeable
J Rodriguez et al.
Genes & development, 13(24), 3179-3184 (2000-01-05)
Autocatalytic activation of initiator caspases is the link between pro-apoptotic signals and the destruction machinery of apoptosis. Activation of caspase-9, which mediates oncogene and drug-induced apoptosis, requires binding to the protein APAF-1. We found that the proteolytic activity of caspase-9
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