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791268P

Avanti

DTPA-BSA (Gd)

DTPA-bis(stearylamide) (gadolinium salt), powder

Synonyme(s) :

(diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt); Gd-DTPA-BSA

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About This Item

Formule empirique (notation de Hill):
C50H94GdN5O8
Numéro CAS:
186796-30-5
Poids moléculaire :
1050.56
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 100 mg (791268P-100mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 791268P

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

DTPA-BSA (Gd) (diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt)) is an amphiphilic molecule with paramagnetic property.

Application

DTPA-BSA (Gd) (diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt)) has been used:
  • in the preparation of nontargeting (NT) gadolinium peptide amphiphile micelles (PAMs) for the magnetic resonance imaging (MRI) of atherosclerotic lesions
  • as a MRI agent in the preparation of lipid-like nanoparticles (LLNs) for small interfering RNA (siRNA) encapsulation
  • as a MRI agent in the preparation of paramagnetic saposin C and dioleylphosphatidylserine (SapC-DOPS) vesicles for imaging glioblastoma multiforme (GBM) tumors

Actions biochimiques/physiologiques

Gd-DTPA-BSA is useful as magnetic resonance imaging (MRI) agent and the gadolinium ion enables the generation of bright images by lowering the longitudinal relaxation time.

Conditionnement

5 mL Amber Glass Screw Cap Vial (791268P-100mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

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Consulter la Bibliothèque de documents

F Jasanada et al.
Bioconjugate chemistry, 7(1), 72-81 (1996-01-01)
In order to use the LDL receptor pathway to target radionuclides to cancer sites for imaging and diagnostic purposes, a labeling procedure of LDL with 111In using the DTPA-bis(stearylamide) (L) has been developed. This bifunctional ligand is intended to be
Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
Luo X, et al.
Nanoscale, 9(4), 1575-1579 (2017)
X Luo et al.
Nanoscale, 9(4), 1575-1579 (2017-01-10)
Multi-functional nanomaterials possess unique properties, facilitating both therapeutic and diagnostic applications among others. Herein, we developed dual-functional lipid-like nanoparticles for simultaneous delivery of mRNA and magnetic resonance imaging (MRI) contrast agents in order to express functional proteins and provide real-time
Geralda A F van Tilborg et al.
Bioconjugate chemistry, 17(3), 741-749 (2006-05-18)
Apoptosis, or programmed cell death, plays an important role in the etiology of a variety of diseases, including cancer and myocardial infarction. Visualization of apoptosis would allow both early detection of therapy efficiency and evaluation of disease progression. To that
Imaging of brain tumors with paramagnetic vesicles targeted to phosphatidylserine
Winter PM, et al.
Journal of Magnetic Resonance Imaging : JMRI, 41(4), 1079-1087 (2015)
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