700014P
Avanti
5β,6β-epoxycholestanol-d7
Avanti Research™ - A Croda Brand
Synonyme(s) :
111115
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About This Item
Formule empirique (notation de Hill):
C27H39O2D7
Numéro CAS:
Poids moléculaire :
409.70
Code UNSPSC :
12352100
Nomenclature NACRES :
NA.25
Produits recommandés
Description
cholestanol, 5β,6β-epoxy-d7
Pureté
>99% (TLC)
Forme
powder
Conditionnement
pkg of 1 × 1 mg (700014P-1mg)
Fabricant/nom de marque
Avanti Research™ - A Croda Brand
Conditions d'expédition
dry ice
Température de stockage
−20°C
Description générale
5β,6β-epoxycholestanol-d7 is the deuterated version of 5β,6β-epoxycholestanol. Cholestanol is a metabolite of cholesterol.
Application
5β,6β-epoxycholestanol-d7 has been used as an internal standard in isotope dilution-mass spectrometry analysis to quantify sterol and oxysterol from mitochondrial samples. It has also been used as an oxysterol standard in high-performance liquid chromatography-mass spectrometry (HPLC-MS method).
Actions biochimiques/physiologiques
Cholestanol levels are elevated in biliary cirrhosis and in cholestasis.
Conditionnement
5 mL Amber Glass Screw Cap Vial (700014P-1mg)
Informations légales
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Souvent commandé avec ce produit
Réf. du produit
Description
Tarif
Code de la classe de stockage
11 - Combustible Solids
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Valentin Mutemberezi et al.
Journal of neuroinflammation, 15(1), 74-74 (2018-03-11)
Oxysterols are cholesterol derivatives that have been suggested to play a role in inflammatory diseases such as obesity, atherosclerosis, or neuroinflammatory diseases. However, the effect of neuroinflammation on oxysterol levels has only been partially studied so far. We used an
Julien Musman et al.
Biochemical pharmacology, 142, 87-95 (2017-06-25)
A major cause of cell death during myocardial ischemia-reperfusion is mitochondrial dysfunction. We previously showed that the reperfusion of an ischemic myocardium was associated with an accumulation of cholesterol into mitochondria and a concomitant strong generation of auto-oxidized oxysterols. The
Annika Mutanen et al.
The American journal of clinical nutrition, 100(4), 1085-1094 (2014-08-08)
Increased serum concentrations of plant sterols, including stigmasterol, during parenteral nutrition (PN) have been linked with serum biochemical signs of intestinal failure-associated liver disease (IFALD), whereas clinical data on their correlation to histologic liver injury have been limited. We studied
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