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CBR00181

Sigma-Aldrich

4-Quinazolinamine

AldrichCPR

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About This Item

Formule empirique (notation de Hill):
C8H7N3
Numéro CAS:
15018-66-3
Poids moléculaire :
145.16
Numéro MDL:
MFCD00092016
Code UNSPSC :
12352200
ID de substance PubChem :
329775476

Forme

solid

Chaîne SMILES 

NC1=C(C=CC=C2)C2=NC=N1

InChI

1S/C8H7N3/c9-8-6-3-1-2-4-7(6)10-5-11-8/h1-5H,(H2,9,10,11)

Clé InChI

DRYRBWIFRVMRPV-UHFFFAOYSA-N

Autres remarques

Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. Sigma-Aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.

NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY; (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE; OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY; WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

Informations légales

Product of ChemBridge Corp.

Pictogrammes

Skull and crossbonesCorrosion
GHS06,GHS05

Mention d'avertissement

Danger

Mentions de danger

H301,H318

Classification des risques

Acute Tox. 3 Oral - Eye Dam. 1

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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L Moyal et al.
The British journal of dermatology, 177(3), 791-800 (2017-03-04)
MicroRNA (miR)-155 contributes to the proliferation of mycosis fungoides (MF) in vitro and is upregulated in tumours of MF compared with early MF lesions. To investigate the contribution of miR-155 to the cancerous phenotype and drug resistance of MF/Sézary cell
Clélia Dental et al.
Journal of immunology (Baltimore, Md. : 1950), 198(3), 1229-1241 (2016-12-21)
A shock-and-kill approach involving the simultaneous treatment of HIV-1-infected patients with latency-reversing agents (LRAs) and combination antiretroviral therapy was proposed as a means to eradicate viral reservoirs. Currently available LRAs cannot discriminate between HIV-1-infected and uninfected cells. Therefore, the risks
Ilaria Cristofaro et al.
Cells, 9(3) (2020-03-19)
Glioblastomas (GBM) are the most aggressive form of primary brain tumors in humans. A key feature of malignant gliomas is their cellular heterogeneity. In particular, the presence of an undifferentiated cell population of defined Glioblastoma Stem cells (GSCs) was reported.
Minghui Liu et al.
Oncotarget, 7(51), 84951-84964 (2016-11-09)
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) is a major challenge to targeted therapy for non-small cell lung cancer (NSCLC). We investigated whether a cyclin D kinase 4/6 (CDK4/6) inhibitor, PD 0332991, could reverse EGFR-TKI resistance
Kota Naito et al.
Biological & pharmaceutical bulletin, 42(4), 631-637 (2019-02-05)
Serotonin (5-hydroxytryptamine; 5-HT) can induce hepatocyte DNA synthesis and proliferation by autocrine secretion of transforming growth factor (TGF)-α through 5-HT2B receptor/phospholipase C (PLC)/Ca2+ and a signaling pathway involving epidermal growth factor (EGF)/TGF-α receptor tyrosine kinase (RTK)/extracellular signal-regulated kinase 2 (ERK2)/mammalian
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