900768

Berkessel-Katsuki epoxidation catalyst

≥98%

• Synonyme(s) : Ti-Berkessel-Katsuki ligand complex, Titanium cis-1,2-diaminocyclohexane salalen catalyst
• Formule empirique (notation de Hill): C₆₄H₄₀F₂₀N₄O₆Ti₂
• Numéro CAS: 2055468-23-8
• Poids moléculaire : 1436.73
• Code UNSPSC : 12161600
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98%
• Forme: powder or crystals
• Pertinence de la réaction: core: titanium; reagent type: catalyst

Description

Application

Developed by Albrecht Berkessel′s lab, this is the first catalyst that allows catalytic enantioselective epoxidation of non-conjugated terminal double bonds with hydrogen peroxide as the oxidant. Eradicating multiple steps and kinetic resolution, this pre-formed chiral ligand-Ti₂O₂ catalyst complex provides a one-step route to enantiopure epoxides that are important intermediates for synthesis of bioactive compounds. Catalyst is recyclable under some conditions. For best results, pentafluorobenzoic acid P5360 or tetra-n-butylammonium hydrogensulfate 155837 is recommended as a co-catalyst.

Autres remarques

Titanium cis-1,2-Diaminocyclohexane Salalen Catalysts of Outstanding Activity and Enantioselectivity for the Asymmetric Epoxidation of Nonconjugated Terminal Olefins with Hydrogen Peroxide

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable