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Sigma-Aldrich

Poly(ethylene glycol) methyl ether thiol

average Mn 2,000, chemical modification reagent thiol reactive, methoxy, thiol

Synonyme(s) :

Polyethylene glycol, Methoxy PEG thiol, Methoxypolyethylene glycol thiol, PEG thiol, mPEG thiol

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About This Item

Formule linéaire :
CH3O(CH2CH2O)nCH2CH2SH
Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

product name

Poly(ethylene glycol) methyl ether thiol, average Mn 2,000

Forme

solid

Poids mol.

average Mn 2,000

Pertinence de la réaction

reagent type: chemical modification reagent
reactivity: thiol reactive

Pf

50-55 °C

Extrémité Ω

thiol

Extrémité α

methoxy

Architecture des polymères

shape: linear
functionality: monofunctional

Température de stockage

−20°C

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Catégories apparentées

Application

  • Surface modification of polyaniline nanorods with thiol-terminated poly (ethylene oxide): This study explores the use of varying molecular weights of poly(ethylene glycol) methyl ether thiol for modifying the surface of polyaniline nanorods, aiming to enhance their dispersibility and functionality (DiTullio et al., 2018).
  • Colorimetric determination of p-phenylenediamine using silver nanoparticles modified with poly (ethylene glycol) methyl ether thiol: The research demonstrates the use of poly(ethylene glycol) methyl ether thiol in modifying silver nanoparticles for the colorimetric determination of p-phenylenediamine, showcasing its application in analytical chemistry (Lee et al., 2017).
  • Facile synthesis and self-assembly of amphiphilic polydimethylsiloxane with poly (ethylene glycol) moieties via thiol-ene click reaction: This article discusses the synthesis and self-assembly of amphiphilic copolymers using thiol-ene click chemistry, emphasizing the versatility of poly(ethylene glycol) methyl ether thiol in creating functional materials (Xia et al., 2015).
  • Determination of polyethylene glycol end group functionalities by combination of selective reactions and characterization by matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS): This study highlights a method for characterizing end group functionalities of poly(ethylene glycol) derivatives using MALDI-TOF MS, where poly(ethylene glycol) methyl ether thiol plays a critical role in the analysis process (Zhang et al., 2014).

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Michael R Dyson et al.
mAbs, 12(1), 1829335-1829335 (2020-10-27)
The early phase of protein drug development has traditionally focused on target binding properties leading to a desired mode of therapeutic action. As more protein therapeutics pass through the development pipeline; however, it is clear that non-optimal biophysical properties can

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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