Accéder au contenu
MilliporeSigma
Toutes les photos(4)

Principaux documents

Voir toute la documentation

56485

Sigma-Aldrich

N-Hydroxysulfosuccinimide sodium salt

≥98% (HPLC), for peptide synthesis

Synonyme(s) :

Hydroxy-2,5-dioxopyrrolidine-3-sulfonate sodium salt, Sulfo-NHS

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Sélectionner une taille de conditionnement

250 MG
261,00 $
1 G
827,00 $
5 G
3 020,00 $

261,00 $

En stockDétails

Devis pour commande en gros
Toutes les photos(4)

Sélectionner une taille de conditionnement

Changer de vue
250 MG
261,00 $
1 G
827,00 $
5 G
3 020,00 $

About This Item

Formule empirique (notation de Hill):
C4H4NNaO6S
Numéro CAS:
106627-54-7
Poids moléculaire :
217.13
Beilstein:
6359129
Numéro MDL:
MFCD00043100
Code UNSPSC :
12352005
ID de substance PubChem :
57651582
Nomenclature NACRES :
NA.22

261,00 $

En stockDétails

Devis pour commande en gros

Nom du produit

N-Hydroxysulfosuccinimide sodium salt, ≥98% (HPLC)

Niveau de qualité

200

Essai

≥98% (HPLC)

Forme

powder

Composition

carbon, 21.57-22.68 (anhydrous)
nitrogen, 6.28-6.61 (anhydrous)

Capacité de réaction

reaction type: Addition Reactions

Impuretés

≤4% water

Application(s)

peptide synthesis

Groupe fonctionnel

imide
sulfonic acid

Chaîne SMILES 

[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O

InChI

1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1

Clé InChI

RPENMORRBUTCPR-UHFFFAOYSA-M

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Catégories apparentées

Application

Le N-hydroxysulfosuccinimide, sel sodique, est un analogue sulfoné de N-hydroxysuccinimide qui est soluble dans l′eau. Il peut réagir dans une réaction de couplage avec les acides carboxyliques en présence de cynamides tels que le 1-éthyl-3-(3-diméthylaminopropyl) cynamide (EDC) pour former des esters actifs de N-hydroxysulfosuccinimide hydrophiles. Ces esters sont utiles dans les expériences de réticulation des protéines.[1][2]

Conditionnement

Flacon en verre sans fond. Le produit se trouve dans un micro-insert conique à l′intérieur du flacon.

Autres remarques

Le sulfo-NHS est utilisé pour préparer des esters actifs hydrophiles, par exemple comme agents de réticulation[3][4]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCM3588
BCCL3044
BCCJ9858
WXBF1499V
WXBF0098V

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

N-hydroxysulfosuccinimide active esters: bis (N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers.
Staros JV
Biochemistry, 21(17), 3950-3955 (1982)
Karen S Cheung Tung Shing et al.
Scientific reports, 8(1), 12457-12457 (2018-08-22)
A direct interaction between the erythropoietin (EPOR) and the beta-common (βc) receptors to form an Innate Repair Receptor (IRR) is controversial. On one hand, studies have shown a functional link between EPOR and βc receptor in tissue protection while others
R Maydelid Trujillo-Nolasco et al.
Materials science & engineering. C, Materials for biological applications, 103, 109766-109766 (2019-07-28)
Radiosynovectomy is a technique used to decrease inflammation of the synovial tissue by intraarticular injection of a β-emitting radionuclide, such as 177Lu, which is suitable for radiotherapy due to its decay characteristics. Drug-encapsulating nanoparticles based on poly lactic‑co‑glycolic acid (PLGA)
P S Anjaneyulu et al.
International journal of peptide and protein research, 30(1), 117-124 (1987-07-01)
N-Hydroxysulfosuccinimide esters are reactive functional groups employed in a variety of protein modification reagents, especially cross-linking reagents. For these compounds, hydrolysis is the most important reaction competing for reaction of the esters with nucleophilic groups in proteins. We have employed
Eloy Povedano et al.
Scientific reports, 8(1), 6418-6418 (2018-04-25)
This paper describes two different electrochemical affinity biosensing approaches for the simple, fast and bisulfite and PCR-free quantification of 5-methylated cytosines (5-mC) in DNA using the anti-5-mC antibody as biorecognition element. One of the biosensing approaches used the anti-5-mC as
Afficher tous les articles scientifiques apparentés

Articles

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What are the storage conditions for product 56485? There are no recommended conditions. Is it Room temp?

    1 answer

    1. As mentioned in the Material Safery Data Sheet, section 7, it is recommended to store under inert gas such as argon or nitrogen. Please see the link below to review the SDS:
      https://www.sigmaaldrich.com/sds/aldrich/56485

      Helpful?

Reviews

No rating value

Active Filters

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique