SCN2A
sodium channel, voltage-gated, type II, alpha subunit
Synonymes:
BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2
Espèce(s):
Human SCN2A (6326), domestic cat SCN2A (101080472), dog SCN2A (478773), chicken SCN2A (395945), naked mole-rat Scn2a (101715020), Horse SCN2A (100051816), domestic guinea pig Scn2a (100716680), sheep SCN2A (101103126), cow SCN2A (539718)
ID UniProtKB:
ID du gène:
- Human(6326) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
- domestic cat(101080472) sodium channel, voltage-gated, type II, alpha subunit
- dog(478773) sodium channel, voltage-gated, type II, alpha subunit
- chicken(395945) sodium channel, voltage-gated, type II, alpha subunit
- naked mole-rat(101715020) sodium channel, voltage-gated, type II, alpha subunit
- Horse(100051816) sodium channel, voltage-gated, type II, alpha subunit
- domestic guinea pig(100716680) sodium channel, voltage-gated, type II, alpha subunit
- sheep(101103126) sodium channel, voltage-gated, type II, alpha subunit
- cow(539718) sodium channel, voltage-gated, type II, alpha subunit
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Small Molecule - Antagonist
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anticorps anti-SCN2A, clone 5H10.2, clone 5H10.2, from mouse,
Espèces réactives
human
Application
western blot
Anti-SODIUM CHANNEL-PAN antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Sodium Channel Antibody, Voltage Gated, Brain Type II, Chemicon®, from rabbit,
Espèces réactives
mouse, rat
Application
immunohistochemistry
western blot
western blot
Anticorps monoclonal anti-canal sodique, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Espèces réactives
mammals
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Numéro du produit
Description
Espèce(s)
Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
esiRNA
Numéro du produit
Description
Espèce(s)