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NFKBIA

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Synonymes:
IKBA, MAD-3, NFKBI
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4792) Summary: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
  • Mouse(18035) nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • Rat(25493) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • naked mole-rat(101709256) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic guinea pig(100723189) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic cat(101090622) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • sheep(780520) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • chicken(396093) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • dog(480291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • cow(282291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Phospho-IκBα-Ser32/36 Antibody, clone 1I11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-IKB α Antibody, clone 6O8, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-p-IκBα-Ser32 Antibody, clone 11D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, feline, human, monkey, porcine
Application
affinity binding assay
flow cytometry

immunocytochemistry

inhibition assay

western blot
Anti-phospho-IkappaB-α (pSer32/36) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Phospho-IκBα-S32/36 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
I?Bα, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Nfkbia,
Espèce(s)
mouse