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MRE11A

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

Synonymes:
ATLD, HNGS1, MRE11, MRE11B
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4361) Summary: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(17535) meiotic recombination 11 homolog A (S. cerevisiae)
  • Rat(64046) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • domestic guinea pig(100721147) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • naked mole-rat(101709211) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Domestic Rabbit(100356946) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • sheep(101114806) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Horse(100060936) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • domestic cat(101086923) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • dog(494006) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Zebrafish(406637) meiotic recombination 11 homolog A (S. cerevisiae)
  • chicken(395555) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-MRE11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-MRE11A antibody produced in mouse, clone 3H4-F4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-MRE11A antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-MRE11A antibody produced in mouse, clone 1D8-A6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Mirin, ≥98% (HPLC), powder,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Mre11a,
Espèce(s)
mouse
MISSION® esiRNA, targeting human MRE11,
Espèce(s)
human