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KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

Synonymes:
EAG, EAG1, Kv10.1, h-eag
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3756) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(16510) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Rat(65198) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • cow(281881) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • chicken(421381) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic cat(101093161) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • dog(490277) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Horse(100051219) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • sheep(101120348) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Domestic Rabbit(100340515) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic guinea pig(100719620) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • naked mole-rat(101706330) potassium voltage-gated channel, subfamily H (eag-related), member 1

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Levofloxacin, 98.0-102.0% anhydrous basis (HPLC),
Espèce(s)
human
Sparfloxacine, ≥98.0% (HPLC),
Espèce(s)
human
Triméthoprime, ≥98.5%,
Espèce(s)
human, rat
Triméthoprime, ≥99.0% (HPLC),
Espèce(s)
human, rat
Ofloxacin, fluoroquinolone antibiotic,
Espèce(s)
rat, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-Potassium Channel EAG-1 Antibody, Chemicon®, from rabbit,
Espèces réactives
rat
Application
western blot
Anti-Potassium Channel Kv10.1 (EAG-1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Espèces réactives
human, mouse, rat
Application
western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Nitrendipine, >95%, powder,
Espèce(s)
human, rat
Pimozide, ,
Espèce(s)
human, mouse, rat
Nifedipine, ≥98% (HPLC), powder,
Espèce(s)
rat, mouse, human
Quinidine, anhydrous,
Espèce(s)
mouse, human, rat
Quinidine, crystallized, ≥98.0% (dried material, NT),
Espèce(s)
mouse, human, rat