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G005454

SFC Analysis of Aminoglutethimide Enantiomers on Astec® Cellulose DMP

application for SFC

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About This Item

test parameters

column: Astec Cellulose DMP, 25 cm x 4.6 mm I.D., 5 μm particles (51099AST)
mobile phase: [A] CO2; [B] methanol containing 0.1% DEA in CO2; (75:25, A:B)
flow rate: 3 mL/min
pressure: 1740 psi (120 bar)
detector: UV, 230 nm
injection: 5 μL
sample: 2 mg/mL in methanol

suitability

application for SFC

application(s)

pharmaceutical (small molecule)

Analysis Note

This application demonstrates the ability of the Astec® Cellulose DMP column to separate Aminoglutethimide enantiomers via Supercritical Fluid Chromatography. DMPC-derivatized cellulose is widely used for chiral separations by SFC, both analytical and prep. The Astec® Cellulose DMP works well in SFC mode, providing rapid separations with excellent selectivity.

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyte

Description
    DL-Aminoglutethimide

analytical column

Product No.
Description
Pricing

standard

Product No.
Description
Pricing

A9657

DL-Aminoglutethimide

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