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Supelco

Discovery® HS F5 (3 µm) HPLC Columns

L × I.D. 2 cm × 2.1 mm Supelguard Guard Cartridge, pkg of 2 ea, Guard Cartridge holder required for use

Synonym(s):

Discovery Pentafluorophenyl PFP HPLC Guard-Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® HS F5 Supelguard Cartridge, 3 μm particle size, L × I.D. 2 cm × 2.1 mm

material

stainless steel column

Agency

suitable for USP L43

product line

Discovery®

feature

endcapped

packaging

pkg of 1 kit

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

2 cm × 2.1 mm

surface area

300 m2/g

matrix

fully porous particle

matrix active group

PFP (pentafluorophenyl) phase

particle size

3 μm

pore size

120 Å

operating pH

2-8

application(s)

food and beverages

compatibility

use to protect Discovery HS F5

separation technique

reversed phase

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Application

Discovery® HS F5 supelguard cartridge may be used with Discovery HS F5 column for high performance liquid chromatographic analysis of tranexamic acid and rocuronium bromide in human plasma samples after extraction using solid-phase microextraction technique.

Footnote

Kit includes one cartridge, a stand-alone holder, a piece of tubing, 2 nuts and ferrules.

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Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Development of SPME method for concomitant sample preparation of rocuronium bromide and tranexamic acid in plasma.
Gorynski K, et al.
Journal of Pharmaceutical and Biomedical Analysis, 92, 183-192 (2014)
Jennie Wang et al.
Journal of pharmaceutical and biomedical analysis, 124, 267-273 (2016-03-13)
An HPLC method for the assay of a DNA topoisomerase inhibitor, LMP776 (NSC 725776), has been developed and validated. The stress testing of LMP776 was carried out in accordance with International Conference on Harmonization (ICH) guidelines Q1A (R2) under acidic
Jana Maláková et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 853(1-2), 265-274 (2007-04-10)
Galantamine, an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii, Amaryllidaceae) and related species, is employed in human medicine for the treatment of various neuromuscular and neurodegenerative diseases. After the administration, the products of oxidative biotransformation
Umberto M Battisti et al.
Journal of chromatography. A, 1443, 152-161 (2016-03-30)
A "heart-cut" two-dimensional achiral-chiral liquid chromatography triple-quadrupole mass spectrometry method (LC-LC-MS/MS) was developed and coupled to in vivo cerebral microdialysis to evaluate the brain response to the chiral compound (±)-7-chloro-5-(3-furanyl)-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide ((±)-1), a potent positive allosteric modulator (PAM) of AMPA receptor.
Lucie Havlíková et al.
Talanta, 76(3), 597-601 (2008-07-01)
A pentafluorophenylpropyl (PFPP) stationary phase was for the first time tested for the simultaneous determination of triamcinolone acetonide, its degradation product triamcinolone and two preservatives, methylparaben, and propylparaben. A new simple isocratic reversed phase HPLC method with UV detection, using

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