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WH0153743M1

Sigma-Aldrich

Monoclonal Anti-PPP1R2P3 antibody produced in mouse

clone 2G11, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-MGC87149, Anti-protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2G11, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG1κ

GenBank accession no.

BC066922

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PPP1R2P3(153743)

General description

Protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 3 (PPP1R2P3) is expressed in sperms and the gene encoding it is localized on human chromosome 5.

Immunogen

PPP1R2P3 (AAH66922, 1 a.a. ~ 205 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MAASTASHRPIKGILKNKTSTTSSMVASAEQPRRSVDEELSKKSQKWDEINILATYHPADKGYGLMKIDEPSPPYHSMMGDDEDACRDTETTEAMAPGILAKKLAAAEGLEPKYRIQEQESSGEEDSDLSPEEREKKRQFEMRRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADGESMNTEESNQGSTPSDQQQNKLRSS

Biochem/physiol Actions

The expression of protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 3 (PPP1R2P3) has been shown to be inhibited in Huntington′s disease, Parkinson′s disease and Alzheimer′s disease.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Valerio Costa et al.
Frontiers in genetics, 3, 231-231 (2012-11-03)
Neurodegenerative disorders and cancer are severe diseases threatening human health. The glaring differences between neurons and cancer cells mask the processes involved in their pathogenesis. Defects in cell cycle, DNA repair, and cell differentiation can determine unlimited proliferation in cancer
Luis Korrodi-Gregório et al.
BMC cell biology, 14, 15-15 (2013-03-20)
Protein Ser/Thr Phosphatase PPP1CC2 is an alternatively spliced isoform of PPP1C that is highly enriched in testis and selectively expressed in sperm. Addition of the phosphatase inhibitor toxins okadaic acid or calyculin A to caput and caudal sperm triggers and

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