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SML0247

Sigma-Aldrich

Rizatriptan benzoate salt

≥98% (HPLC)

Synonym(s):

MK-462, N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt

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10 MG
$105.00

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10 MG
$105.00

About This Item

Empirical Formula (Hill Notation):
C15H19N5 · C7H6O2
CAS Number:
145202-66-0
Molecular Weight:
391.47
MDL number:
MFCD00866224
UNSPSC Code:
12352200
PubChem Substance ID:
329825257
NACRES:
NA.77

$105.00

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Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: ≥5 mg/mL

storage temp.

room temp

SMILES string

OC(=O)c1ccccc1.CN(C)CCc2c[nH]c3ccc(Cn4cncn4)cc23

InChI

1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)

InChI key

JPRXYLQNJJVCMZ-UHFFFAOYSA-N

Gene Information

human ... HTR1B(3351) , HTR1D(3352)

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Show Differences

1 of 4

This Item
1604880Y0001302N1415
Rizatriptan benzoate salt ≥98% (HPLC)

SML0247

Rizatriptan benzoate salt

Rizatriptan benzoate United States Pharmacopeia (USP) Reference Standard

1604880

Rizatriptan benzoate

Rizatriptan benzoate European Pharmacopoeia (EP) Reference Standard

Y0001302

Rizatriptan benzoate

Naratriptan hydrochloride ≥98% (HPLC)

N1415

Naratriptan hydrochloride

form

powder

form

-

form

-

form

powder

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

100

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

H2O: ≥5 mg/mL

solubility

-

solubility

-

solubility

H2O: ≥10 mg/mL

Biochem/physiol Actions

Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine.
Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360

Precautionary Statements

P201 - P308 + P313

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
033M4734V
022M4725V

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Robert MacNeill et al.
Bioanalysis, 4(10), 1163-1173 (2012-06-02)
In the context of matrix effects in bioanalytical LC-MS/MS, a speculative link between free cholesterol, the recoveries of the compound from three common extraction procedures, and response enhancement was qualitatively investigated. Injections on-column of cholesterol both in solution and extracts
Zhao Dong et al.
Brain research, 1368, 151-158 (2010-10-26)
The trigeminovascular nociception induced by electrical stimulation of the dura mater surrounding the superior sagittal sinus in anesthetized animals has been widely used as a model for investigation of the pathophysiology of vascular headache such as migraine. However, little is
Anthony J Rodgers et al.
Headache, 51(3), 356-368 (2010-11-03)
To examine total migraine freedom (TMF), defined as pain freedom and absence of associated symptoms, using rizatriptan clinical trial data and to explore advantages of TMF as a single primary composite efficacy endpoint. The FDA has set a higher regulatory
Rizatriptan is effective for headache in a patient with meningeal carcinomatosis.
Takeshi Satow et al.
Journal of pain and symptom management, 41(5), e2-e4 (2011-04-05)
Types of colitis based on histology.
Muhammed Sherid et al.
Disease-a-month : DM, 57(9), 457-489 (2011-09-29)
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