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SMB01006

Sigma-Aldrich

Dechlorogriseofulvin

≥90% (LC/MS-ELSD)

Synonym(s):

3′,4,6-Trimethoxy-5′-Methylspiro[1-Benzofuran-2,4′-Cyclohex-2-Ene]-1′,3-Dione, 7-Dechlorogriseofulvin, griseofulvin impurity B [EP impurity]

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About This Item

Empirical Formula (Hill Notation):
C17H18O6
CAS Number:
Molecular Weight:
318.32
UNSPSC Code:
12352205
NACRES:
NA.25

Assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

318.32

solubility

water: slightly soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C17H18O6/c1-9-5-10(18)6-14(22-4)17(9)16(19)15-12(21-3)7-11(20-2)8-13(15)23-17/h6-9H,5H2,1-4H3/t9-,17+/m1/s1

InChI key

QPCYNIYZPDJCMB-XLFHBGCDSA-N

General description

Dechlorogriseofulvin, is a polyketide natural compound and a derivative of griseofulvin, an antifungal agent. This secondary metabolite is naturally derived from Penicillium sp. but has also been reported from endophytic fungi such as Nigrospora sp. It has been found to exhibit various biological activities, including antifungal, antibacterial, antitumor, and anti-inflammatory properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Dechlorogriseofulvin functions by inhibiting microtubule assembly, causing disruption in cell division and growth.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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J H Zhao et al.
World journal of microbiology & biotechnology, 28(5), 2107-2112 (2012-07-19)
An endophytic fungus was isolated from the root of the medicinal plant Moringa oleifera Lam. Based on analyzing the rDNA sequence, the fungus was identified as Nigrospora sp. This is the first report of the isolation of endophytic Nigrospora from

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