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SCP0259

Sigma-Aldrich

Vasoactive Intestinal Constrictor / β Endothelin mouse

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About This Item

Empirical Formula (Hill Notation):
C116H161N27O32S4
Molecular Weight:
2573.94
UNSPSC Code:
12352200
NACRES:
NA.32

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Cys-Ser-Cys-Asn-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp

Application

Endothelin-2 (Vasoactive Intestinal Constrictor), mouse, a vaso-constricting peptide, is used in studies of the maintenance, protection and hyper-pigmentation of the epidermis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Javier Adur et al.
Peptides, 28(5), 1083-1094 (2007-04-24)
We examined the expression profiles of vasoactive intestinal contractor/endothelin-2 (VIC/ET-2) at both gene and peptide level in skin irradiated with different ultraviolet wavelengths. We found that VIC/ET-2 gene expression is sensitive only to ultraviolet-C (UVC) irradiation and has an immediate
Eiichi Kotake-Nara et al.
Biochemical and biophysical research communications, 357(1), 168-173 (2007-04-10)
We previously found that endothelin-2/vasoactive intestinal contractor (ET-2/VIC) greatly increased in mouse epidermis after birth. In the present study, we evaluated whether ET-2/VIC expression was associated with the calcium-induced differentiation of cultured mouse keratinocytes. The differentiation induction was revealed by
Eiichi Kotake-Nara et al.
TheScientificWorldJournal, 6, 176-186 (2006-02-24)
This paper reviews the local hormone endothelin-2 (ET-2), or vasoactive intestinal contractor (VIC), a member of the vasoconstrictor ET peptide family, where ET-2 is the human orthologous peptide of the murine VIC. While ET-2/VIC gene expression has been observed in
Edie I Crosse et al.
Cell stem cell, 27(5), 822-839 (2020-09-19)
Hematopoietic stem cells (HSCs) first emerge in the embryonic aorta-gonad-mesonephros (AGM) region. Studies of model organisms defined intersecting signaling pathways that converge to promote HSC emergence predominantly in the ventral domain of the dorsal aorta. Much less is known about

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