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Key Documents

SBR00083

Sigma-Aldrich

Lasalocid A Sodium Salt

≥95% (H-NMR), powder

Synonym(s):

Avatec, Bovatec, Sodium Lasalocid A

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About This Item

Empirical Formula (Hill Notation):
C34H53NaO8
CAS Number:
Molecular Weight:
612.77
UNSPSC Code:
51101500

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Quality Level

Assay

≥95% (H-NMR)

form

powder

color

white to off-white

mp

180 °C

antibiotic activity spectrum

Gram-positive bacteria

Mode of action

cell membrane | inhibits

storage temp.

−20°C

SMILES string

CC[C@H]([C@@H]1[C@H](C[C@@](O1)(CC)[C@H]2CC[C@@]([C@@H](O2)C)(CC)O)C)C(=O)[C@@H](C)[C@H]([C@H](C)CCC3=C(C(=C(C=C3)C)O)C(=O)[O-])O.[Na+]

InChI

InChI=1S/C34H54O8.Na/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39;/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39);/q;+1/p-1/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+;/m1./s1

General description

Lasalocid A Sodium Salt is an antibiotic which belongs to the class of compounds called ionophores which can transport ions across cell membranes. Lasalocid A Sodium Salt acts as an ionophore for monovalent cations across the cell membranes of bacteria and protozoa.

Biochem/physiol Actions

Lasalocid A Sodium Salt disrupts the balance and energy metabolism in certain bacteria and protozoa. As an ionophore for monovalent cations, Lasalocid A Sodium Salt acts by binding to and transporting these ions across the cell membranes of bacteria and protozoa. This leads to the disruption of the ion balance across the cell membranes, which is essential for the normal functioning of cellular processes, including energy metabolism. Disruption of energy metabolism ultimately leads to the inhibition of essential cellular processes and bacterial or protozoal cell death. The selective toxicity of Lasalocid A Sodium Salt against certain bacteria and protozoa is due to the specific properties of their cell membranes, which are different from those of mammalian cells.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Muta. 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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