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SAB5700315

Sigma-Aldrich

Anti-Phospho-MAP3K7-S412 antibody produced in rabbit

Synonym(s):

CSCF, FMD2, MAP3K7, MEKK7, TAK1, TGF1a

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100 μL
$437.00

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100 μL
$437.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$437.00


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biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

53
56
64
67

species reactivity

human

concentration

0.99 mg/ml

technique(s)

western blot: 1:500-1:2000

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This Item
SAB5700312SAB5700083SAB2109108
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

UniProt accession no.

O43318

UniProt accession no.

Q02750

UniProt accession no.

Q02750

UniProt accession no.

-

mol wt

53, 64, 56, 67

mol wt

40, 43

mol wt

40, 43

mol wt

41 kDa

technique(s)

western blot: 1:500-1:2000

technique(s)

western blot: 1:500-1:2000

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:1000-1:3000

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-8 μg/mL, western blot: 1 μg/mL

General description

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Immunogen

A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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