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SAB4502826

Sigma-Aldrich

Anti-SNAP25 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

SN25, SNAP, SNP25, SUP, Super protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 23 kDa

species reactivity

mouse, human, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... SNAP25(6616)

General description

Anti-SNAP25 antibody detects endogenous levels of total SNAP25 protein.
The SNAP25 (synaptosome associated protein 25) gene is mapped to human chromosome 20p12.2. The encoded protein belongs to the family of SNARE (small ILF3/NF90-associated RNA E) complex.

Immunogen

The antiserum was produced against synthesized peptide derived from human SNAP25.

Immunogen Range: 151-200

Biochem/physiol Actions

SNAP25 (synaptosome associated protein 25) protein is involved in extracellular trafficking and mediates the process of exocytosis and endocytosis by promoting fusion of vesicles with the plasma membrane. SNAP25 is needed for rapid excitatory and inhibitory neurotransmission of neurons producing glutamate and GABA (gamma aminobutyric acid).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.
Rasnitsyn A
PLoS ONE, 12(6), 1-24 (2017)
Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder.
Kustanovich V
Molecular Psychiatry, 8(3), 309-315 (2003)

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