S1068

SB-215505

solid, >98% (HPLC)

• Synonym(s): 6-Chloro-5-methyl-1-5-quinolycarbamoyl-indoline
• Empirical Formula (Hill Notation): C₁₉H₁₆N₃OCl
• CAS Number: 162100-15-4
• Molecular Weight: 337.80
• MDL number: MFCD05664741
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278573
• NACRES: NA.77

Properties

• Assay: >98% (HPLC)
• form: solid
• color: off-white
• solubility: DMSO: soluble ~11 mg/mL at 60 °C; H₂O: insoluble
• originator: GlaxoSmithKline
• storage temp.: 2-8°C
• SMILES string: Cc1cc2CCN(C(=O)Nc3ccnc4ccccc34)c2cc1Cl
• InChI: 1S/C19H16ClN3O/c1-12-10-13-7-9-23(18(13)11-15(12)20)19(24)22-17-6-8-21-16-5-3-2-4-14(16)17/h2-6,8,10-11H,7,9H2,1H3,(H,21,22,24)
• InChI key: BPVGSWDWIRIUME-UHFFFAOYSA-N
• Gene Information: human ... HTR2B(3357)

Description

Biochem/physiol Actions

Selective 5-HT_2B serotonin receptor antagonist; 100-fold higher affinity at 2B versus 2C.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Glaxo­Smith­Kline

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves