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Key Documents

R7753

Sigma-Aldrich

Rhapontin

≥99% (HPLC), from rhubarb

Synonym(s):

3,3′,5-Trihydroxy-4′-methoxystilbene 3-O-β-D-glucoside, NSC 43321, Rhaponticin

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About This Item

Empirical Formula (Hill Notation):
C21H24O9
CAS Number:
Molecular Weight:
420.41
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:

biological source

rhubarb

Assay

≥99% (HPLC)

storage temp.

2-8°C

SMILES string

COc1ccc(\C=C\c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1O

InChI

1S/C21H24O9/c1-28-16-5-4-11(8-15(16)24)2-3-12-6-13(23)9-14(7-12)29-21-20(27)19(26)18(25)17(10-22)30-21/h2-9,17-27H,10H2,1H3/b3-2+/t17-,18-,19+,20-,21-/m1/s1

InChI key

GKAJCVFOJGXVIA-DXKBKAGUSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Jinlong Chen et al.
Planta medica, 75(5), 472-477 (2009-02-25)
We isolated several stilbene compounds including rhaponticin (3',5-dihydroxy-4'-methoxystilbene 3- O-beta- D-glucopyranoside) from extracts of rhubarb rhizomes. These compounds showed significant hypoglycemic effects in streptozotocin (STZ)-induced type 1 diabetic rats and mice. In this study, we investigated the effect of rhaponticin
Yang Sun et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 87, 171-178 (2011-12-16)
Rhaponticin (RHA) possesses a variety of pharmacological activities including potent antitumor, antitumor-promoting, antithrombotic, antioxidant and vasorelaxant effects. In the solvation effect, RHA exhibited bathochromic shift in emission spectra with the increasing solvent polarity. The binding between RHA and HSA was
Yang Sun et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102, 194-199 (2012-12-12)
Rhaponticin (RH) possesses a variety of pharmacological activities including potent antitumor, antitumor-promoting, antithrombotic, antioxidant and vasorelaxant effects. The fundamental photophysics of RH is not well understood. In this work, solvent effect on the photoluminescence behavior of RH was studied by
Xiaoyan Wang et al.
Phytochemical analysis : PCA, 23(6), 684-688 (2012-05-16)
The official rhubarb species have frequently been investigated for their hydroxyanthraquinone components and associated pharmacological properties. However, other unofficial rhubarb species were rarely studied until polyhydroxystilbenes (PHS), which commonly occur in the unofficial rhubarb, revealed a range of potential bioactivities.
Narae Kim et al.
Medical mycology, 51(1), 45-52 (2012-06-06)
Rhapontigenin, an aglycone of rhapontin, was produced by biotransformation and we investigated its antifungal activity against Candida albicans, one of the most important opportunistic fungal pathogens. Rhapontigenin is found to have, in vitro, inhibitory activity with a minimal inhibitory concentration

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