PLA0115

Rabbit anti-DNA-PKcs Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): DNA-PK catalytic subunit, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, IMD26, XRCC7, complementing 1, hyper-radiosensitivity of murine scid mutation, p350, p460
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: human
• technique(s): immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:1,000- 1:10,000
• accession no.: NP_008835.5
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... DNA-PKcs(5591)

Description

Immunogen

The epitope recognized by PLA0115 maps to a region between residues 2050 and 2100 of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable