P3905
pGlu-His-Pro
≥97% (TLC)
Synonym(s):
TRH, Thyrotropin releasing hormone
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C16H21N5O5
CAS Number:
Molecular Weight:
363.37
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥97% (TLC)
storage temp.
−20°C
SMILES string
OC(=O)C1CCCN1C(=O)C(Cc2cnc[nH]2)NC(=O)C3CCC(=O)N3
Gene Information
mouse ... Trhr(22045)
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
E C Griffiths et al.
Molecular and cellular endocrinology, 18(1), 59-67 (1980-04-01)
Specific radioimmunoassays for thyrotrophin-releasing hormone (TRH) and deamido-TRH (TRH-OH) were used to investigate the inactivation of TRH by subcellular fractions from rat hypothalamus. TRH-OH was rapidly formed from TRH by an amidase present only in the supernatant fraction at an
Concentrations of thyrotropin-releasing hormone (TRH) and deamido-TRH, and TRH deamidase activity in brain.
C H Emerson et al.
Endocrinology, 107(2), 443-449 (1980-08-01)
L Ouafik et al.
Annales d'endocrinologie, 47(1), 43-44 (1986-01-01)
This study allows the indirect demonstration of a precursor for TRH in pancreatic extracts of 2-days old rats. The sequential treatment of these extracts with trypsin and carboxypeptidase A is followed by a large increase in Pyroglutamyl Histidine Proline (TRH-OH).
J López-Barneo et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(20), 8150-8154 (1990-10-01)
The interaction of thyrotropin-releasing hormone (TRH) and its physiological metabolite TRH-OH with Na+ channels was studied in enzymatically dissociated guinea pig septal neurons by using the whole-cell variant of the patch-clamp technique. In about 60% of the cells tested, the
C G Scanes et al.
Neuroendocrinology, 40(1), 33-38 (1985-01-01)
Thyrotropin-releasing hormone (TRH) stimulated in vivo growth hormone (GH) release in conscious and anesthetized young domestic fowl. The administration of the presumed metabolites of TRH, deamido-TRH (TRH-OH) and histidyl-proline diketopiperazine (HPD), was followed by small but significant (p less than
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service