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M4507

Sigma-Aldrich

4-Methylumbelliferyl p-trimethylammoniocinnamate chloride

powder

Synonym(s):

MUTMAC

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About This Item

Linear Formula:
C22H22NO4Cl
CAS Number:
34197-47-2
Molecular Weight:
399.87
MDL number:
MFCD00063503
UNSPSC Code:
12352204
PubChem Substance ID:
24896925
NACRES:
NA.32

Assay

≥97% (TLC)

form

powder

solubility

water: pyridine, 1:1: 50 mg/mL

storage temp.

−20°C

SMILES string

Cl.CC1=CC(=O)Oc2cc(OC(=O)\C=C\c3ccc(cc3)[N](C)(C)C)ccc12

InChI

1S/C22H22NO4.ClH/c1-15-13-22(25)27-20-14-18(10-11-19(15)20)26-21(24)12-7-16-5-8-17(9-6-16)23(2,3)4;/h5-14H,1-4H3;1H/b12-7+;

InChI key

KYYHCHQCEWDCBB-RRAJOLSVSA-N

Substrates

Fluorometric substrate for α-chymotrypsin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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G W Jameson et al.
The Biochemical journal, 131(1), 107-117 (1973-01-01)
Several esters of 4-methylumbelliferone and 2-naphthol were synthesized and examined as possible spectrofluorimetric titrants for bovine alpha-chymotrypsin, trypsin, thrombin, Factor Xa and for subtilisin Novo. 4-Methylumbelliferyl p-guanidinobenzoate hydrochloride (MUGB) is a satisfactory titrant for alpha- and beta-trypsin, thrombin and Factor

Articles

Chymotrypsin

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

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