VLDL (Very low density lipoprotein) may be used to study the mechanisms and effects of very low density receptors (VLDLR). VLDL is used as a potential source of fatty acids that support cardiac energy metabolism. VLDL is often studied to differentiate its effects from those of chylomicrons.
Inhibits DNA synthesis in lymphocytes activated by the nonspecific mitogen concanavalin A (Con A).
Arteriosclerosis, thrombosis, and vascular biology, 33(8), 1986-1993 (2013-05-25)
Resistin-like molecule (RELM) β is a secretory protein homologous to resistin and reportedly contributes to local immune response regulation in gut and bronchial epithelial cells. However, we found that activated macrophages also express RELMβ and thus investigated the role of
Biochemical and biophysical research communications, 285(2), 393-399 (2001-07-11)
Human very-low-density lipoprotein (VLDL) inhibits DNA synthesis in lymphocytes activated by the nonspecific mitogen concanavalin A (Con A). We studied the effects of VLDL on lymphocyte activation (IL-2 receptor expression), cell cycle progression, and production of IL-2 and of IL-4
The Yale journal of biology and medicine, 85(1), 19-28 (2012-03-31)
The LDLR family of proteins is involved in lipoproteins trafficking. While the role of LDLR in cardiovascular disease has been widely studied, only recently the role of other members of the LDLR proteins in lipoprotein homeostasis and atherosclerosis has emerged.
Arteriosclerosis, thrombosis, and vascular biology, 32(5), 1079-1086 (2012-04-21)
Steady increase in the incidence of atherosclerosis is becoming a major concern not only in the United States but also in other countries. One of the major risk factors for the development of atherosclerosis is high concentrations of plasma low-density
Journal of lipids, 2011, 189876-189876 (2011-07-21)
The heart is a major consumer of energy and is able to utilise a wide range of substrates including lipids. Nonesterified fatty acids (NEFA) were thought to be a favoured carbon source, but their quantitative contribution is limited because of
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