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H7160

Sigma-Aldrich

Hepatitis C virus core antigen−Fluorescein

~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Quality Level

Assay

≥95% (SDS-PAGE)

mol wt

22 kDa (plus 114 kDa β-Gal tag)

concentration

~1 mg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

hepatitis C virus ... HCVgp1(951475)

Biochem/physiol Actions

Positive control for HCV antibodies.

Other Notes

HCV core antigen [2-192]-Galactosidase-tagged, fluorescein conjugate.

Physical form

Solution in 1.2 M Urea, 20 mM Tris-HCl, pH 8.0, 10 mM 2-mercaptoethanol.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Inés Romero-Brey et al.
mBio, 6(4), e00759-e00759 (2015-07-15)
Induction of membrane rearrangements in the cytoplasm of infected cells is a hallmark of positive-strand RNA viruses. These altered membranes serve as scaffolds for the assembly of viral replication factories (RFs). We have recently shown that hepatitis C virus (HCV)
Margaret A Scull et al.
PLoS pathogens, 11(11), e1005297-e1005297 (2015-11-21)
The hepatitis C virus (HCV) p7 protein is required for infectious virus production via its role in assembly and ion channel activity. Although NMR structures of p7 have been reported, the location of secondary structural elements and orientation of the

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