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GW22770

Anti-MAPK7 (ab2) antibody produced in chicken

Name: Anti-MAPK7 (ab2) antibody produced in chicken
Brand: SIGMA

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

biological source

chicken

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

manufacturer/tradename

Genway 15-288-22770

technique(s)

western blot: suitable

NCBI accession no.

NP_002740.2

UniProt accession no.

Q13164

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAPK7(5598)

Immunogen

Immunogen Sequence: GI # 20986497, sequence 341-570

Recombinant mitogen-activated protein kinase 7 isoform 1

Application

Anti-MAPK7 (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Mitogen-activated protein kinase 7 (also known as MAP kinase 7) is an enzyme encoded by the MAPK7 gene in humans and is mapped to chromosome 17 band p11.2. It belongs to mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. MAPK7 is involved in degeneration of nucleus pulposus. Expression of MAPK7 may act as a valuable indicator for predicting lung cancer risk in smokers.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Differential expression of extracellular-signal-regulated kinase 5 (ERK5) in normal and degenerated human nucleus pulposus tissues and cells.

Weiguo Liang et al.

Biochemical and biophysical research communications, 449(4), 466-470 (2014-05-27)

Extracellular-signal-regulated kinase 5 (ERK5) is a member of the mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. However, the expression of ERK5 and its role in degenerated

A functional polymorphism in the promoter of ERK5 gene interacts with tobacco smoking to increase the risk of lung cancer in Chinese populations.

Fuman Qiu et al.

Mutagenesis, 28(5), 561-567 (2013-06-28)

Mitogen/extracellular signal-regulated kinase-5 (MEK5)/extracellular signal-regulated protein kinase-5 (ERK5) pathway plays a pro-oncogenic role in tumourigenesis by anticell apoptosis, promoting cell proliferation and differentiation in response to extracellular stimuli. As overexpressed MEK5/ERK5 is involved in the development of lung cancer, we

Assignment of big MAP kinase (PRKM7) to human chromosome 17 band p11.2 with somatic cell hybrids.

S M Purandare et al.

Cytogenetics and cell genetics, 83(3-4), 258-259 (1999-03-11)

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