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G8148

Sigma-Aldrich

Gly-Arg-p-nitroanilide dihydrochloride

unokinase and plasmin substrate

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About This Item

Empirical Formula (Hill Notation):
C14H21N7O4 · 2HCl
CAS Number:
125455-61-0
Molecular Weight:
424.28
MDL number:
MFCD00083360
UNSPSC Code:
12352204
PubChem Substance ID:
24895332
NACRES:
NA.32

Assay

≥98% (TLC)

form

powder

solubility

methanol: 20 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl.NCC(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc(cc1)N(=O)=O

InChI

1S/C14H21N7O4.ClH/c15-8-12(22)20-11(2-1-7-18-14(16)17)13(23)19-9-3-5-10(6-4-9)21(24)25;/h3-6,11H,1-2,7-8,15H2,(H,19,23)(H,20,22)(H4,16,17,18);1H

InChI key

MGFMNXNZZCRYAQ-UHFFFAOYSA-N

Substrates

Substrate for plasmin and urokinase

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Flourogenic peptide amide substrates for the estimation of plasminogen activators and plasmin.
W Nieuwenhuizen et al.
Analytical biochemistry, 83(1), 143-148 (1977-11-01)
Thiago P Nascimento et al.
Anais da Academia Brasileira de Ciencias, 92(4), e20200882-e20200882 (2020-12-10)
The industrial demand for proteolytic enzymes is stimulating the search for new enzyme sources. Fungal enzymes are preferred over bacterial enzymes, and more effective and easier to extract. The aim of this work was to evaluate the potential of protease
Thiago Pajeú Nascimento et al.
Bioprocess and biosystems engineering, 40(8), 1209-1219 (2017-05-14)
Fibrinolytic proteases are enzymes that degrade fibrin. They provide a promising alternative to existing drugs for thrombolytic therapy. A protease isolated from the filamentous fungus Mucor subtilissimus UCP 1262 was purified in three steps by ammonium sulfate fractionation, ion exchange
Ning Luan et al.
Thrombosis and haemostasis, 117(6), 1031-1039 (2017-03-10)
The repugnatorial glands of millipedes release various defensive chemical secretions. Although varieties of such defensive secretions have been studied, none of them is protein or peptide. Herein, a novel factor Xa (FXa) inhibitor named joannsin was identified and characterised from repugnatorial glands

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