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G8129

Sigma-Aldrich

Guanosine 2′:3′-cyclic monophosphate sodium salt

~97%

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About This Item

Linear Formula:
C10H11N5O7PNa
CAS Number:
Molecular Weight:
367.19
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:

Assay

~97%

solubility

H2O: soluble

storage temp.

−20°C

SMILES string

[Na].NC1=NC(=O)c2ncn(C3OC(CO)C4OP(O)(=O)OC34)c2N1

InChI

1S/C10H12N5O7P.Na.H/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-6-5(3(1-16)20-9)21-23(18,19)22-6;;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);;

InChI key

HOTMPXGKAYLTBL-UHFFFAOYSA-N

Caution

Do not confuse with the common guanosine 2′- & 3′- monophosphate (mixed isomers).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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J M Pérez-Cañadillas et al.
Biochemistry, 37(45), 15865-15876 (1998-12-08)
The electrostatic behavior of titrating groups in alpha-sarcin was investigated using 1H NMR spectroscopy. A total of 209 chemical shift titration curves corresponding to different protons in the molecule were determined over the pH range of 3.0-8.5. Nonlinear least-squares fits
K Hamada et al.
Mutation research, 326(1), 71-82 (1995-01-01)
U5 snRNA can induce both transformation and chromosome aberrations of cells. The polypurine tract, GGAGAGGAA, of the RNA has been suggested to participate in both phenomena. In vitro transcription expected to give this polypurine oligoribonucleotide was associated with cleavage of
Ryan Morgan et al.
Journal of bacteriology, 188(21), 7335-7343 (2006-10-20)
Multiple environmental cues have been shown to trigger biofilm detachment, the transition from surface-attached, highly organized communities known as biofilms to the motile lifestyle. The goal of this study was to identify a gene product involved in sensing environmental cues
Robert P Ryan et al.
Molecular microbiology, 63(2), 429-442 (2007-01-24)
Cyclic di-GMP is a second messenger with a role in regulation of a range of cellular functions in diverse bacteria including the virulence of pathogens. Cellular levels of cyclic di-GMP are controlled through synthesis, catalysed by the GGDEF protein domain
L Jovine et al.
Structure (London, England : 1993), 8(5), 527-540 (2000-05-10)
Bacterial signal recognition particle (SRP), consisting of 4.5S RNA and Ffh protein, plays an essential role in targeting signal-peptide-containing proteins to the secretory apparatus in the cell membrane. The 4.5S RNA increases the affinity of Ffh for signal peptides and

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