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EMU069941

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Pax5

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTCCCAAAGTGGTGGAAAAAATCGCTGAGTACAAACGCCAAAACCCTACCATGTTTGCCTGGGAGATCAGGGACCGGCTGTTGGCAGAGCGAGTCTGTGACAATGACACTGTGCCCAGCGTCAGCTCCATCAACAGGATCATTCGGACAAAAGTACAGCAGCCCCCCAATCAGCCGGTCCCAGCTTCCAGTCACAGCATAGTGTCTACAGGCTCCGTGACGCAGGTGTCATCGGTGAGCACCGACTCCGCGGGCTCCTCATACTCCATCAGTGGCATCCTGGGCATCACGTCCCCCAGTGCCGACACCAACAAACGCAAGAGGGATGAAGGTATTCAGGAGTCTCCAGTGCCGAATGGCCACTCACTTCCGGGCCGGGACTTCCTCCGGAAGCAGATGCGGGGAGACCTGTTCACACAGCAGCAG

Ensembl | mouse accession no.

ENSMUSG00000014030

NCBI accession no.

NM_008782

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... PAX5(18507) , Pax5(18507)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Kasar et al.
Oncogene, 33(25), 3307-3315 (2013-09-03)
Genetic lesions and other regulatory events lead to silencing of the 13q14 locus in a majority of chronic lymphocytic leukemia (CLL) patients. This locus encodes a pair of critical proapoptotic microRNAs, miR-15a/16-1. Decreased levels of miR-15a/16-1 are critical for the

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