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EHU133151

Sigma-Aldrich

MISSION® esiRNA

targeting human PPP4R2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTCCTGGAAATTCACCAAGCTATACTGAGAGGTCTAATATAAATGGGCCTGGGACACCCAGGCCACTTAATCGACCAAAGGTTTCTTTGTCAGCCCCCATGACAACAAATGGGTTGCCTGAGAGCACAGACAGCAAAGAGGCAAATTTGCAGCAAAATGAGGAGAAAAATCACAGTGACTCTTCGACCTCTGAATCAGAAGTTTCCTCAGTGAGCCCTTTGAAAAATAAACATCCAGATGAAGATGCTGTGGAAGCTGAGGGGCATGAGGTAAAAAGACTCAGGTTTGACAAAGAAGGTGAAGTCAGAGAAACAGCCAGTCAAACGACTTCCAGCGAAATTTCTTCAGTTATGGTAGGAGAAACAGAAGCATCATCTTCATCTCAGGATAAAGACAAAGATAGCCGTTGTACCCG

Ensembl | human accession no.

ENSG00000163605

NCBI accession no.

NM_174907

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... PPP4R2(151987) , PPP4R2(151987)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Pabitra K Parua et al.
Nature communications, 11(1), 4338-4338 (2020-08-30)
Reversible phosphorylation of Pol II and accessory factors helps order the transcription cycle. Here, we define two kinase-phosphatase switches that operate at different points in human transcription. Cdk9/cyclin T1 (P-TEFb) catalyzes inhibitory phosphorylation of PP1 and PP4 complexes that localize

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