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EHU062791

Sigma-Aldrich

MISSION® esiRNA

targeting human TRIM41

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGGATCTAGACCCCGTCACCCCACTGCCCCCGCCTCCAGCCCCTCGGAGGTGCTTCACATGCCCTCAGTGCCGAAAGAGCTTTCCTCGGCGGAGCTTCCGCCCCAACCTGCAGCTGGCCAATATGGTCCAGGTGATTCGGCAGATGCACCCAACCCCTGGTCGAGGGAGCCGCGTGACCGATCAGGGCATCTGTCCCAAACACCAAGAAGCCCTGAAGCTCTTCTGCGAGGTAGACGAAGAGGCCATCTGTGTGGTGTGCCGAGAATCCAGGAGCCACAAACAGCACAGCGTGGTGCCATTGGAGGAGGTGGTGCAGGAGTACAAGGCCAAACTGCAGGGGCACGTGGAACCACTGAGGAAGCACCTGGAGGCAGTGCAGAAGATGAAAGCCAAGGAGGAGAGGCGAGTGACAGAAC

Ensembl | human accession no.

ENSG00000146063

NCBI accession no.

NM_033549

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... TRIM41(90933) , TRIM41(90933)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Shijian Zhang et al.
PloS one, 8(8), e70001-e70001 (2013-08-13)
Tripartite motif (TRIM) proteins constitute a family of over 100 members that share conserved tripartite motifs and exhibit diverse biological functions. Several TRIM proteins have been shown to restrict viral infections and regulate host cellular innate immune responses. In order
Sourav Saha et al.
Cell reports, 33(13), 108569-108569 (2020-12-31)
The present study demonstrates that topoisomerase 3B (TOP3B) forms both RNA and DNA cleavage complexes (TOP3Bccs) in vivo and reveals a pathway for repairing TOP3Bccs. For inducing and detecting cellular TOP3Bccs, we engineer a "self-trapping" mutant of TOP3B (R338W-TOP3B). Transfection with

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