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EHU051441

Sigma-Aldrich

MISSION® esiRNA

targeting human NOV

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCCAGGGCAAATAGTCAAGAAGCCAGTGATGGTCATTGGGACCTGCACCTGTCACACCAACTGTCCTAAGAACAATGAGGCCTTCCTCCAGGAGCTGGAGCTGAAGACTACCAGAGGGAAAATGTAACCTGTCACTCAAGAAGCACACCTACAGAGCACCTGTAGCTGCTGCGCCACCCACCATCAAAGGAATATAAGAAAAGTAATGAAGAATCACGATTTCATCCTTGAATCCTATGTATTTTCCTAATGTGATCATATGAGGACCTTTATATCTGTCTTTTATTTAACAAAAAATGTAATTAACTGTAAACTTGGAATCAAGGTAAGCTCAGGATATGGCTTAGGAATGACTTACTTTCCTGTGGTTTTATTACAAATGCAAATTTCTATAAATTTAAGAAAACAAGTATATAATTTACTTTGTAGACTGTTTCACATTGCACTCATCA

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Po-Chun Chen et al.
Oncotarget, 8(43), 74506-74518 (2017-11-02)
Epithelial-mesenchymal transition (EMT) has received considerable attention as a conceptual paradigm for explaining metastatic behavior during cancer progression. NOV/CCN3 is a matrix-associated protein involved in many cellular functions. Previous studies have shown that CCN3 expression is upregulated in prostate cancer
Jason R Dobson et al.
Cancer cell international, 14, 73-73 (2014-08-15)
For treatment and prevention of metastatic disease, one of the premier challenges is the identification of pathways and proteins to target for clinical intervention. Micro RNAs (miRNAs) are short, non-coding RNAs, which regulate cellular activities by either mRNA degradation or

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