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About This Item
Empirical Formula (Hill Notation):
C7H8N4S
CAS Number:
Molecular Weight:
180.23
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
Recommended Products
form
solid
SMILES string
[H]n1cnc2c(SCC)ncnc12
InChI
1S/C7H8N4S/c1-2-12-7-5-6(9-3-8-5)10-4-11-7/h3-4H,2H2,1H3,(H,8,9,10,11)
InChI key
XTJLAIOQORFEOI-UHFFFAOYSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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B T French et al.
Cancer chemotherapy and pharmacology, 27(3), 171-177 (1990-01-01)
A variety of compounds inhibit the growth and induce differentiation of human promyelocytic leukemia (HL-60) cells. HL-60 subclones that lack the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT) can also be induced to differentiate with purine analogs. Mechanisms by which purine
D S Gibboney et al.
Cancer chemotherapy and pharmacology, 25(3), 189-194 (1989-01-01)
A variety of purine analogs inhibit the growth and induce the differentiation of human promyelocytic leukemia (HL-60) cells that lack the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). Mechanisms by which purine analogs induce differentiation offer unique potential for cancer chemotherapy.
S Namciu et al.
Oncogene, 9(5), 1407-1416 (1994-05-01)
Overexpression of v-ski blocks the terminal differentiation of chicken erythroblasts, and in cooperation with v-sea causes transformation of these cells, indicating that c-ski may play a role in regulating either proliferation or differentiation in hematopoietic cells. We examined c-ski expression
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