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D9772

Sigma-Aldrich

1,2-Dipiperidinoethane

Synonym(s):

1,1′-(1,2-Ethanediyl)bispiperidine

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About This Item

Empirical Formula (Hill Notation):
C12H24N2
CAS Number:
1932-04-3
Molecular Weight:
196.33
EC Number:
217-692-7
UNSPSC Code:
12352103

density

0.92 g/mL at 25 °C (lit.)

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Recent advances in the use of selective neuron-destroying agents for neurobiological research.
A Contestabile et al.
Experientia, 40(6), 524-534 (1984-06-15)
S Levine et al.
Journal of neuropathology and experimental neurology, 39(1), 56-64 (1980-01-01)
Single doses of dipiperidinoethane (DPE) produced symmetrical necrosis in pyriform cortex, amygdala and other areas of gray matter in rats, mice and gerbils. The necrosis was detectable in 10 hours and fully developed in 24 hours. Its distribution and severity
B M Baron et al.
Brain research, 331(1), 164-167 (1985-04-01)
Dipiperidinoethane (DPE) administration produces seizures and CNS lesions. Here we elucidate the cholinergic origin of DPE toxicity. DPE is both an acetylcholinesterase (AChE) inhibitor and a muscarinic antagonist. This dual action negates most of the toxic effects of the compound
Excitatory transmitters and epilepsy-related brain damage.
J W Olney
International review of neurobiology, 27, 337-362 (1985-01-01)
Status epilepticus in the limbic system: biochemical and pathological changes.
R C Collins et al.
Advances in neurology, 34, 277-288 (1983-01-01)
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