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B1682

Sigma-Aldrich

BAD from mouse

≥70% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

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About This Item

MDL number:
MFCD03456151
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Quality Level

200

description

full-length murine Bad with an N-terminal histidine-tag.

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

31 kDa

UniProt accession no.

Q61337

storage temp.

−20°C

Gene Information

mouse ... Bad(12015)

Biochem/physiol Actions

Bad, a pro-apoptotic factor, is a member of the Bcl-2 family. Cytokine-induced phosphorylation of Bad results in it being sequested in the cytosol. In the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.

Physical form

Supplied as a solution in phosphate buffered saline containing 250 mM imidizole and 50% glycerol.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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