Journal of medicinal chemistry, 30(2), 445-448 (1987-02-01)
The synthesis of the amino acid sequence found in bovine prothrombin precursor 13-29 (PTP 13-29) has been achieved by solid-phase synthesis of the bis(acetamidomethyl)-protected linear peptide followed by cyclization to the monomeric disulfide. Synthesis of the disulfide bond was achieved
Vitamin K-dependent carboxylase is found in the liver, where it is involved in the synthesis of four blood coagulation factors and protein C. The hepatic enzyme has partly been purified and several mechanisms have been postulated for the vitamin K-dependent
Vitamin K-dependent carboxylation.
P A Friedman et al.
The International journal of biochemistry, 19(1), 1-7 (1987-01-01)
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