A2787
N-Acetyl-D-galactosamine–Agarose
saline suspension
Synonym(s):
N-Acetyl Galactosamine
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About This Item
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biological source
plant
form
saline suspension
technique(s)
affinity chromatography: suitable
matrix
cross-linked 4% beaded agarose
matrix activation
epoxy
matrix attachment
6-hydroxy
matrix spacer
12 atoms
capacity
≥6 mg/mL binding capacity (lectin from Glycine max)
suitability
suitable for chromatography
storage temp.
2-8°C
Application
N-Acetyl-D-galactosamine is an agarose used in affinity chromatography, protein chromatography and in carbohydrate matrices. N-Acetyl-D-galactosamine has been used to study periodontal disease and to facilitate the design of potent small-molecule ice recrystallization inhibitors. N-Acetyl-D-galactosamine has also been used to demonstrate a molecular shuttle between extracellular and cytoplasmic space allows for monitoring of GAG biosynthesis.
Physical form
Suspension in 0.5 M NaCl containing preservative.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hiroko Hoshi et al.
Biochimica et biophysica acta, 1820(9), 1391-1398 (2012-01-24)
Cell surface proteoglycans play vital functional roles in various biological processes such as cell proliferation, differentiation, adhesion, inflammation, immune response, sustentation of cartilage tissue and intensity of tissues. We show here that serglycin-like synthetic glycopeptides function efficiently as a molecular
A new histochemical approach for studying sperm cell surfaces.
Ngo, L., et al.
Acta Histochemica, 106(1), 21-28 (2003)
Anna K Balcerzak et al.
Bioorganic & medicinal chemistry letters, 22(4), 1719-1721 (2012-01-24)
The β-d-galactosyl-(1,3)-α-N-acetyl-d-galactosamine disaccharide is present in antifreeze glycoproteins (AFGPs). Analogs of this disaccharide including the β-linked (1,3)-, (1,4)-, and (1,6)-galactosyl-N-acetyl galactosamine and the β-(1,3)-galactosyl-galactoside were synthesized and evaluated for ice recrystallization inhibition (IRI) activity. The results from this study demonstrate
Reynald Tremblay et al.
Transgenic research, 20(2), 345-356 (2010-06-19)
Soybean agglutinin (SBA) is a specific N-acetylgalactosamine-binding plant lectin that can agglutinate a wide variety of cells. SBA has great potential for medical and biotechnology-focused applications, including screening and treatment of breast cancer, isolation of fetal cells from maternal blood
A Loukas et al.
Current biology : CB, 9(15), 825-828 (1999-09-02)
Many parasitic nematodes live for surprisingly long periods in the tissues of their hosts, implying sophisticated mechanisms for evading the host immune system. The nematode Toxocara canis survives for years in mammalian tissues, and when cultivated in vitro, secretes antigens
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