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A0894

Sigma-Aldrich

5′-Amino-2′,5′-dideoxy-5-iodouridine

~96%

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About This Item

Empirical Formula (Hill Notation):
C9H12IN3O4
CAS Number:
Molecular Weight:
353.11
UNSPSC Code:
12352204

Assay

~96%

storage temp.

2-8°C

Biochem/physiol Actions

Potent inhibitor of herpes simplex virus (HSV) in cell culture.

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Y C Cheng et al.
Journal of virology, 15(5), 1284-1285 (1975-05-01)
5-Amino-2,5-dideoxy-5-iodouridine, a nel thymidine analogue, is a potent inhibitor of herpes simplex virus type 1 replication. In contrast to most other nucleoside analogues which possess antiviral activity, 5-amino-2,5-dideoxy-5-iodouridine exhibits little, if any, cellular toxicity. Preliminary evidence suggests that 5-amino-2,5-dideoxy-5-iodouridine selectively

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