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55496

Sigma-Aldrich

Hydroxyapatite

′high resolution′

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

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About This Item

Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
1306-06-5
Molecular Weight:
502.31
EC Number:
215-145-7
MDL number:
MFCD00010904
UNSPSC Code:
12352200
PubChem Substance ID:
57651499

capacity

≥1.2 mg/g, dry material binding capacity (DNA)
 ≥15 mg/g, dry material binding capacity (BSA)

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Other Notes

DNA purification; Analysis of DNA damage; Stabilization of double-standard DNA

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rapid isolation of mouse DNA from cells in tissue culture.
W Meinke et al.
Analytical biochemistry, 58(1), 82-88 (1974-03-01)
A hydroxylapatite batch assay for quantitation of cellular DNA damage.
P M Kanter et al.
Analytical biochemistry, 97(1), 77-84 (1979-08-01)
The nucleic acid-hydroxylapatite interaction. I. Stabilization of native double-stranded deoxyribonucleic acid by hydroxylapatite.
H G Martinson
Biochemistry, 12(1), 139-145 (1973-01-02)
Bjarke Viberg et al.
Acta orthopaedica, 84(3), 254-259 (2013-04-19)
Elderly patients with displaced femoral neck fractures are commonly treated with a hemiarthroplasty (HA), but little is known about the long-term failure of this treatment. We compared reoperation rates for patients aged at least 75 years with displaced femoral neck
Frank G Lyons et al.
Clinical orthopaedics and related research, 472(4), 1318-1328 (2014-01-05)
Treatment of segmental bone loss remains a major challenge in orthopaedic surgery. Traditional techniques (eg, autograft) and newer techniques (eg, recombinant human bone morphogenetic protein-2 [rhBMP-2]) have well-established performance limitations and safety concerns respectively. Consequently there is an unmet need
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