The closest to MNF6 (detects CK 5, 6, 8, 17, and possibly 19) is CK cocktail AE1/AE3, which detects all but CK17. Oscar detects CK 7, 8, 18, and 19.
313M-1
Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody
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1 ML
$180.00
1 ML
$180.00
0.1 ML
$246.00
0.1 ML
$246.00
7 ML
$439.00
7 ML
$439.00
0.5 ML
$442.00
0.5 ML
$442.00
1 ML
$608.00
1 ML
$608.00
15 ML
$805.00
25 ML
$1,320.00
25 ML
$1,320.00
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1 ML
$180.00
1 ML
$180.00
0.1 ML
$246.00
0.1 ML
$246.00
7 ML
$439.00
7 ML
$439.00
0.5 ML
$442.00
0.5 ML
$442.00
1 ML
$608.00
1 ML
$608.00
15 ML
$805.00
25 ML
$1,320.00
25 ML
$1,320.00
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
100
500
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
AE1 & AE3, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (313M-14)
vial of 0.5 mL concentrate (313M-15)
bottle of 1.0 mL predilute (313M-17)
vial of 1.0 mL concentrate (313M-16)
bottle of 7.0 mL predilute (313M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1κ
control
breast, colon, prostate, skin
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... KRT1(3848)
General description
Anti-cytokeratin cocktail (AE1 & AE3) is a broad-spectrum keratin antibody cocktail. It is composed of mouse monoclonal antibody AE1 that recognizes acidic type I keratins and AE3 that reacts with basic type II keratins. Both clones were generated using epidermal keratin as immunogen. This antibody is useful for identifying cells of epithelial origin and detects most carcinomas of different primarysites. This antibody cocktail can cross-react with other intermediate filaments, such as glialfibrillary acidic protein, giving false-positive staining in glial tumors.
Quality
 IVD |  IVD |  IVD |  RUO |
Linkage
Cytokeratin Cocktail Positive Control Slides, Product No. 313S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Other Notes
For Technical Service please contact: 800-665-7284 or email: [email protected]
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Customers Also Viewed
V K Kriho et al.
Virchows Archiv : an international journal of pathology, 431(2), 139-147 (1997-08-01)
Several studies have shown that immunoenzymatic staining of formalin-fixed, paraffin-embedded astrocytomas with keratin antibodies frequently yields positive labelling, but no biochemical evidence of keratin expression in astrocytomas has been reported. We have investigated the presence of keratin in astrocytoma and
Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations.
D Cooper et al.
Laboratory investigation; a journal of technical methods and pathology, 52(3), 243-256 (1985-03-01)
A M Gown et al.
American journal of clinical pathology, 84(4), 413-424 (1985-10-01)
A panel of monoclonal antibodies to human intermediate filament proteins was tested on an unselected series of 246 neoplasms. The antibody panel includes two different anti-cytokeratin antibodies, an anti-vimentin antibody, and an anti-neurofilament antibody (Gown and Vogel, Am J Pathol
H Battifora
The American journal of surgical pathology, 12 Suppl 1, 24-42 (1988-01-01)
The past few years have seen great progress in our knowledge of the biology and the chemistry of intermediate filaments and other filamentous proteins. This has translated into the development of antibodies that, together with new, highly sensitive immunohistochemical methods
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Is there a broad spectrum CK cocktail that is an equivalent to the Dako MNF116?
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