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T1550000

α-Tocopherol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(±)-α-Tocopherol, DL-all-rac-α-Tocopherol, Vitamin E

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About This Item

Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
Molecular Weight:
430.71
Beilstein:
94012
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

Agency

EP

API family

tocopherol

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

density

0.950 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. α-Tocopherol, an active form of vitamin E, is a lipid-soluble antioxidant found in whole grains, nuts, and oils. It is known to scavenge reactive oxygen species by interacting with lipids during oxidative stress.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup


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ANTIOXIDANTS-Role of Antioxidant Nutrients in Defense Systems
Encyclopedia of food sciences and nutrition, 282-289 (2003)
Quantitative determination of underivatized alpha-tocopherol in cow milk, vitamin and multivitamin drugs by GC-FID
Kadioglu Y, et al.
Chromatographia, 70(3-4), 665-670 (2009)
Flow injection spectrophotometric determination of vitamin E in pharmaceuticals, milk powder and blood serum using potassium ferricyanide-Fe (III) detection system
Jadoon S, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 21(6), 712-715 (2010)
The role of alpha-tocopherol in plant stress tolerance
Munne-Bosch S
Journal of Plant Physiology, 162(7), 743-748 (2005)
Kirsten G Coupland et al.
Movement disorders : official journal of the Movement Disorder Society, 29(13), 1606-1614 (2014-01-01)
Parkinson's disease (PD) is a neurodegenerative disorder for which environmental factors influence disease risk and may act via an epigenetic mechanism. The microtubule-associated protein tau (MAPT) is a susceptibility gene for idiopathic PD. Methylation levels were determined by pyrosequencing of

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