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41647

Sigma-Aldrich

Dimethyl sulfoxide

puriss., absolute, over molecular sieve (H2O ≤0.005%), ≥99.5% (GC)

Synonym(s):

DMSO

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About This Item

Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
EC Number:
MDL number:
UNSPSC Code:
12191502
PubChem Substance ID:

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

grade

absolute
puriss.

Assay

≥99.5% (GC)

autoignition temp.

573 °F

quality

over molecular sieve (H2O ≤0.005%)

expl. lim.

42 %, 63 °F

impurities

≤0.005% water
water

refractive index

n20/D 1.479 (lit.)
n20/D 1.479

bp

189 °C (lit.)

mp

16-19 °C (lit.)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Clive M Gray et al.
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Hannes Hahne et al.
Nature methods, 10(10), 989-991 (2013-08-27)
We report that low percentages of dimethylsulfoxide (DMSO) in liquid chromatography solvents lead to a strong enhancement of electrospray ionization of peptides, improving the sensitivity of protein identification in bottom-up proteomics by up to tenfold. The method can be easily
Guillermo Garcia-Effron et al.
Antimicrobial agents and chemotherapy, 53(1), 112-122 (2008-10-29)
A detailed kinetic characterization of echinocandin inhibition was performed for mutant 1,3-beta-d-glucan synthase enzymes from clinical isolates of Candida albicans with nine different FKS1 mutations resulting in high MICs. Among 14 mutant Fks1p enzymes studied, the kinetic parameters 50% inhibitory
Bing Zheng et al.
Organic letters, 15(7), 1690-1693 (2013-03-23)
A direct and efficient approach for palladium-catalyzed arylation of aryl and alkyl methyl sulfones with aryl bromides has been developed. The catalytic system affords arylated sulfones in good to excellent yields (73-90%).

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