ABS1009

Anti-HSD17B7 Antibody

• Synonym(s): 3-keto-steroid reductase|17-beta-hydroxysteroid dehydrogenase 7|17-beta-HSD 7|Estradiol 17-beta-dehydrogenase 7|PRL receptor-associated protein|PRAP|HSD17B7
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 300
• clone: polyclonal
• species reactivity: human, hamster, mouse, rat, bovine
• technique(s): immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable

Description

General description

3-keto-steroid reductase (UniProt Q62904; EC 1.1.1.270, EC 1.1.1.62; also known as PRAP, 17-beta-HSD 7, PRL receptor-associated protein, Estradiol 17-beta-dehydrogenase 7, 17-beta-hydroxysteroid dehydrogenase 7, Hydroxysteroid dehydrogenase 17 beta, type 7) is encoded by the Hsd17b7 gene in rat (Entrez Gene ID 29540). Hsd17b7 protein is most abundantly expressed in ovaries of pregnant animals and functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids, as well as as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol. Cat. No. ABS1009, Anti-HSD17B7, is a rabbit polyclonal antiserum raised against native rat protein, and shows reactivity toward rat, human, mouse, hamster, and bovine species (PMID 1425419).

Immunogen

Purified protein corresponding to rat HSD17B7.

Application

Anti-HSD17B7 Antibody is an antibody against HSD17B7 for use in Western Blotting, Immunohistochemistry, Immunocytochemistry.

Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected HSD17B7 in mouse ovary sections and human adrenal gland tissue.
Western Blotting Analysis: A representative lot detected HSD17B7 in rat, mouse, cow, hamster, bovine,

Quality

Evaluated by Western Blotting in mouse stomach tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected HSD17B7 in 10 ug of mouse stomach tissue lysate.

Other Notes

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1